HTTP/1.1 200 OK Cache-Control: no-cache, private Content-Type: text/html; charset=UTF-8 Date: Sun, 29 Nov 2020 09:43:51 GMT 日日干夜夜操北条麻妃
Jump to main content
Jump to site search

Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

[p?n'demik]
Vocal duo: Thompson Square

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

在就业增长前景最好的州当中,西部各州占据了主导地位。在排名前十位的州当中,只有两个州位于密西西比河以东,分别是佛罗里达州和乔治亚州。其他排名前五位的州是科罗拉多州(预计年度就业增长2.6%)、北达科他州(2.5%)和佛罗里达州(2.5%)。
长期以来,中国增长数据的人为平稳广为人知,但以购买力平价汇率计算,如今中国毫无疑问是世界第一大经济体,因此这些统计数据传达的信息带来了更广泛的影响。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

“由于这些情况不会一夜间消失,2017年贸易基本没有希望复苏,”里尔宁说。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 六月十大油漆涂料品牌排行榜曝光
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

当然在接下来的一段时间中里还有很多事情要解决,还会有更多的推测,更多的享受。祝我们所有的读者度过一个安全愉快的假期,迎来一个崭新快乐的篮球之年。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

据二十一世纪教育研究院副院长熊丙奇表示,公费留学生都签署了一项协议,如果完成学业后不回国的话,必须偿还政府的资助款项。
adj. 确实的,保障的,有自信的 动词assure的过
Call Me By Your Name
你咋不上天呢?

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Best film and best director. Surprisingly, Nolan has never received a directing nomination from the Academy.
Executives in the finance and real estate industries have the highest pay, according to figures from the 1,894 listed companies that announced their annual financial reports in 2016.
“…brought his dog.”
厌倦了一成不变的生活?何不去探险,让身心重新焕发活力?毫无疑问,南极洲会是个好去处。亲眼目睹企鹅嬉戏,成群结队的海鸟飞过天空,要比观看电视纪录片更令人兴奋。想象一下,置身于雄伟冰山和原生态山脉构成的世界中,是多么刺激和美好的一件事啊!但要注意的是,南极洲地处极地,因此行前要做好充足准备。保暖靴、防寒外套、手套、羊毛袜和帽子一样都不能少。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

il不+legal合法的→不合法的

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

['kriminl]

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
2. The 2012 Ig Nobel Peace Prize

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Will José Antonio Meade be the next president of Mexico
200911/88511.shtml

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

“有个人在Facebook上公开辞职。”
Last year was the hottest on earth since record-keeping began in 1880, scientists reported on Friday, underscoring warnings about the risks of runaway greenhouse gas emissions and undermining claims by climate change contrarians that global warming had somehow stopped.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

10.专注工作,调节平衡
I can't stop thinking that these children are my age, that it makes a tremendous difference where you are born, that I could be one of those children living in the Favellas of Rio; I could be a child starving in Somalia; a victim of war in the Middle East or a beggar in India. 我永远不能忘记这些和我同龄的孩子,当你出生的时候,他和我们真的很不相同,我也许生活在贫民窟,也可能是终日饿着肚子的小孩,也可能是中东战争的牺牲品,或者印度的小乞丐。
Las Vegas Shooting
Together, the world’s 10 highest-paid actresses tallied a combined $205 million between June 1, 2015 and June 1, 2016, before management fees and taxes, Forbes said.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

This year, the average sales price for an apartment in New York City topped $1 million, a milestone with far-reaching implications. As the city’s population soars, prices and buildings are rising in neighborhoods that missed the last housing boom.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

还有哪对系列电影的荧幕情侣可以像《暮光之城》的克里斯汀?斯图尔特和罗伯特?帕丁森这样成功开创戏路呢?两个人都成为了影坛名角。帕丁森在最新作品《好时光》中延续了他近年来这种让人几乎认不出的造型风格。在《迷失Z城》中,他把自己打扮成胡子蓬乱的眼镜男,如今他又把头发染成亚麻色,变身为一个试图在纽约完美做案,结果却让患有发育性残疾的弟弟(本?萨弗迪饰)被捕的银行抢劫犯。他试图用盗取的钱来给弟弟交保释金,结果麻烦接踵而至。很多的麻烦。除了饰演弟弟一角外,本?萨弗迪还和自己的哥哥约书亚?萨弗迪共同执导了这部电影。《好时光》入围了今年戛纳电影节的主竞赛单元,参与角逐金棕榈奖。该片于11月3日在日本上映,11月17日在英国和爱尔兰上映,11月23日在希腊上映。(资料来源:A24制片公司)
然而,她辩称,亚洲ETF流动性较低的问题反映了基金分销体系未能激励中介销售ETF。她说:“我认为没有快速的解决办法,但如果亚洲转向收费模式,会出现起色。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 佛山LED照明产业“颓势”分析
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Official data indicates a total of 81 feature length films, including 47 Chinese titles, surpassed the 100 million yuan box office threshold.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

中国房价在今年初曾以9.6%的同比增速快速上涨,但此后随着经济放缓以及很多中等规模城市遭遇房产供应过剩,房价一直在下跌。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

周二公布的数据显示,去年12月,中国规模以上工业企业利润同比下降8%,是2011年末以来的最大降幅。11月数据的同比下滑幅度为4.2%。
jar
Summly and Yahoo refused to comment on the deal’s terms.
昨日发布的央行数据显示,中国外汇储备上月出现有记录以来第三大单月降幅。这重燃了人们对于中国遭遇资本外流的担忧,此前中国外汇储备似乎企稳。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

年龄:50岁
In fact, create a hard and fast rule to keep work and job searching separate. That means no sneaking out for a phone interview. No browsing job boards. No applying or networking with your work email address. "You don't watch porn at work, and you don't work on your résumé at work," Kay says. "You just don't."
单词virtue 联想记忆:
以美元计算的话,这一跌幅就更加明显了,上个月出口同比下滑11.2%至1774.8亿美元。这一跌幅不仅超过了去年12月1.4%的跌幅,也超过了下滑1.8%的预期。这是自去年3月下滑15%以来的最大跌幅。
3.现役军人

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

37| “Anomalisa” (Charlie Kaufman/Duke Johnson)|
She was also recognised for being the youngest recipient of the Ripple of Hope Award from the Robert F. Kennedy Center for her charity work.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 居然之家发力“大家居”
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Despite it being not that different from the typical bottle opener, the BOx does have a nice design made with stainless steel and solid wood.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

n. 喜剧,滑稽,幽默事件

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Ms Lewis urged people to contact family, neighbours or an animal shelter if they were no longer able to care for their pets.
But the change in Wall Street’s — and Silicon Valley’s — appreciation of Mr Cook is down to more than just the 70m iPhones Apple is expected to sell this quarter or the $42bn in sales generated in the previous.
荷兰合作银行表示,在本月唐纳德.特朗普(Donald Trump)当选美国总统后,该行对美国的前景持谨慎态度。
在360000个网红账号中,女性达到74%。而87.8%的网红年龄都在17-33岁之间,89%的网红接受过高等教育。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

St. Vincent “Digital Witness” (Loma Vista/Republic)
我曾经看到经理们因为工作环境大都是男性所以没有雇佣一位女性。他们不会在乎那个女人有多聪明,多厉害。她就是不合适。
This makes China the country with the second most number of universities included in the Global 400 Subjects, according to the QS rankings. This is only after the United States, which has 164 universities included in the Global 400 subjects. The UK comes third at 78 universities.
立场:和员工分享300万美元奖金

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

['trit?bl]
The fastest growing start-ups tend to be global in their outlook. The immigration restrictions already imposed by President Trump in the US and those under consideration as part of the UK’s separation from the EU are likely to be a hindrance in the coming year for hiring.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

台风哈维
作为宝莱坞片酬最高的女演员之一,迪皮卡·帕度柯妮是2015全球十大美女榜的季军。在印度,她是性感女神、时尚偶像。帕度柯妮在印度各类魅力女性榜上的排名都很靠前。完美的身材、深邃的眼神和迷人的微笑使她脱颖而出。她是许多品牌的代言人,包括天梭、索尼数码相机、雀巢咖啡、沃格眼镜、美宝莲和百事可乐等等。
黑莓在周三下午的一份声明中表示:“黑莓尚未与三星进行过任何潜在的收购谈判。黑莓的方针是不对谣言和揣测加以评论,因此我们也不会对此做出进一步说明。”
2006年,哈茨与现任丈夫凯文共同创办了在线票务平台Eventbrite。自成立以来,这家公司先后从红杉资本(Sequoia Capital)和老虎全球基金(Tiger Global Management)等公司获得了总计1.4亿美元的投资。今年9月,它的票务销售总额达到了20亿美元。创业让哈茨不得不在与人沟通时运用坦率、且具有合作性的对话方式。她说:“我必须学会如何寻求帮助。所有人都认为创业是勇敢的举动,但我认为,更需要勇气的事情是,把自己摆到众人面前,同时努力达成协作。”
Yet institutions matter, too, because they set the rules of the game.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

STEP 9: BE SURE to tell everyone to shut up on a daily basis, it's endearing you know
The 25 most common passwords have been released by Splashdata which makes password management applications.
Will the UK economy be the slowest-growing in the G7

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Manufacturing has held up better, with profits growing 6.5 per cent, while profits from utilities such as electricity, heat and water grew 17 per cent, boosted by lower energy prices.
“Selling out!” “Pandering to the Americans!” The cries went up immediately when the official selection was announced. The list of directors crossing over to make films in English was a long one including the Italians Matteo Garrone and Paolo Sorrentino, Yorgos Lanthimos of Greece, Norway's Joachim Trier and even Guillaume Nicloux of France, a country whose cultural establishment is highly sensitive to the creeping Anglophone menace. The argument goes that Cannes is supposed to be a haven for world cinema; for English, there is Hollywood. But does it really matter? Films at Cannes in languages other than French or English play with subtitles in both languages – and that's a lot of text to deal with.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 专家称:解决租房问题主要靠市场
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

补救办法:虽然自己当老板的想法很诱人,但并不是每个人都适合创业。创造属于自己的事业,让家人过上幸福生活,改善顾客的生活,这些听起来肯定很浪漫,但漫长的工作时间、没有闲暇时间、承担资金风险,身兼老板、职员、营销人员、会计和门卫等多个职位于一身,这些你能承受吗?如果你喜欢稳定的工作和专注于某项具体任务而不是身兼多职,又或者你不喜欢冒险,你就无法想象整天为工作忙碌的生活。如果你属于以上情况,那么创业并不适合你。
我们就是要打造开放的高地、投资的热土,和世界共享发展机遇。
China's Ministry of Education (MOE) said at a news conference that most of the world's foreign students who study abroad are from China.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: “月欠族”过度消费危害不容小觑
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

[k?n'sist?ntli]
答:其实我并不怎么关心作品火不火的,就是专注于自己的作品而已。每次我关注的就是要怎样用最好地推进剧情而已。我关注的是行为和故事,不是受欢迎程度。
高盛将大派红包,饱受各方抨击一个月,然后静悄悄地干回自己的老本行--挣钱。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

7.Drones

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

认真思考一下:未来的经历能提高你的知识和技能吗?它是否会让你接触到新的观点,认识不同的人?(这些都是支持你对机会说“Yes”的好理由!)你需要为了管理团队或与经验更加丰富的同事共事而培养新技巧吗?如果答案是肯定的,那就接受这种挑战,走出你的舒适区。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

9. Smiling
2. 宾夕法尼亚大学沃顿商学院

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

['stresf?l]
Song “Embrace Happiness”(Kelly Chen)
The Jungle Book will be released worldwide on April 15, 2016.
An Obama tweet, published in August after racial violence rocked Charlottesville, Virginia was the second most-shared this year, according to Twitter, with more than 1.7 million retweets.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Julia Hartz
China's 16 listed banks have cut their dividend payouts for the past year amid slowing net profit growth.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

“今年榜单有趣的地方之一是,尽管网站都开始实行更严的密码设定政策,位数少的密码仍出现在今年的榜单上。”
8. “Mad Max: Fury Road”(George Miller)

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

WhatsApp had been particularly ad-averse before its sale to Facebook. CEO Jan Koum kept a note from co-founder Brian Acton taped to his desk to remind him of the company’s core values. It read: “No Ads! No Games! No Gimmicks!”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 绿色建材发展即将驶入“快车道”
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

根据电影监管机构数据显示,中国电影票房销售额在去年同比了增长48.7%
Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.
戴假牙的角色
20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告:“如果你上亚马逊,看到什么精彩的黑白电影卖三美元,或者其他什么外国电影和鲜为人知的电影,赶快买下来,因为它就要绝版了,他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式,迪克森警告说。而下载的美丽新世界(又名电子销售)明年将是好年头。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 东莞住宅供应量降至年内低点
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

时间:2010-01-26 编辑:vicki
你一定有一个连走路时都念念不忘的怪癖。你只想聊这个。瞧着吧,观众会被你帅到的。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

如果一个“推文幼稚的像个幼儿园小朋友”一样最年长的人,都可以当选总统,那为什么反过来不试一下,看看年轻人能否当选并明智地执政?
1)Thank You: Common courtesy? Sure. But tell me this: When was the last time you forgot (or rejected) gratitude? Whether given in private or public, a sincere ‘thanks’ creates goodwill. Don’t forget your mother’s advice: “Say please.” People are always happier doing a favor than taking an order.
Anyone can have a bad day at the office, but this disappointing performance at Christie’s followed an old masters sale in July that took in 19 million against a low estimate of 31.5 million.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

但他认为自己任教的经历非常宝贵,可以让他很快适应新的职业阶段。
无人驾驶汽车是当下炒作得最火的行业,这类汽车的倡导者已成为冗词赘语的世界级领军人物。埃隆?马斯克(Elon Musk)自称“要在一个安全系数超出人工驾驶数量级倍数的一体化平台上专注于全自动驾驶的实现”。(就是说特斯拉肯定能防止车祸的发生)。
It is the eighth straight year that the metropolis has led Chinese cities in terms of consumer spending.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

尽管英国商学院的排名平均上升了两位,但法国商学院的排名平均下降了一位——法国是商学院数量最多的欧洲国家。里昂商学院(EMLyon Business School)由于跌出MBA榜单之外,整体排名下降了15位,同时北方高等商学院(Edhec Business School)由于未能进入EMBA榜单,整体排名下降了8位。
筹备IPO交易的公司正在增多,尽管今年在美国高调上市的Snap(旗下拥有Snapchat)表现不佳,同时投资者担忧欧元不断走强可能遏制欧洲企业的盈利复苏。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

A total of 1,300 fugitives suspected of economic crimes, 347 of whom were corrupt officials, returned to China from abroad to face justice last year, according to the country's top discipline watchdog.
影片可能太过非主流,不具有获得大奖的影响力。
谎言9:对,我在高中足球队里就是个捣蛋鬼!说谎原因:我想让自己在别人的眼里更加闪亮。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

贸易往来令中国该月贸易顺差达到408.2亿美元,比预期低大约72亿美元,也比11月份修正后442.3亿美元的水平(修正前该数字为446.1亿美元)低了36亿美元左右。以人民币计的这一顺差则为2754亿元人民币。
China will "fasten the seat belt" and prevent any "acute outburst" of financial risks on the track for maintaining medium-high growth speed.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

I am so excited to be hosting the Oscars for the second time. You know what they say - the third time's the charm.
US News also offers subject-focused rankings, which include popular fields such as computer science, economics and business and engineering.
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 1月 发展“长期租赁”市场
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

9、《神奇动物在哪里》

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

4. Outsourcing placement services.
Scientists have long investigated stem cells' potential for growing hearts, and they reached a major milestone this year when they created heart tissue than can beat on its own.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

你是不是今年遇到过一些糟糕的面试?这项调查肯定能让你振奋起来,除非你恰好也经历过类似窘境。人力资源公司OfficeTeam要求来自北美的600名管理者描述他们在2014年见过的最令人尴尬的面试失误。以下是他们给出的答案。
In 2002, Marc Cherry (the creator of Desperate Housewives) was watching the news with his mother in her home. The lead story on the news that day (and many days before) was the Andrea Yates trial. Andrea was on trial for drowning her five children in the bathtub. Marc turned to his mother and asked, "Could you imagine a woman being so desperate that she would murder her own children?"

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 建材价格涨涨涨 市场成交难难难
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

He was responsible for monitoring how many cupcake aficionados were allowed in the store at one time. Of course Magnolia Bakery isn't exactly complaining. The store proudly displays memorabilia from the show on the walls of their many locations. Today, Magnolia Bakery is known for their banana pudding, but they will always owe their initial success to Carrie Bradshaw and a red velvet cupcake.
Dua Lipa, 'Dua Lipa'

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

即便缩减购债规模的行动进展顺利,今年大部分时间美联储也会在是否最早于2015年开始加息的问题上举棋不定。
The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 环保家居建材消费旺盛
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

n. 码,密码,法规,准则

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

People (read: your boss) will notice if you go from sporting a uniform of jeans and a T-shirt to showing up in a tailored suit on interview day. This is all the more reason to take the day off from work to interview, but if you don't, dress as usual at the office. And then, Foss says, "leave the premises, and stop in a McDonald's parking lot on the way to the interview to change."
Others are Ouyeel, a unit of Shanghai Baosteel Group that provides financing for steel traders; and Small Entrepreneur, part of China Merchants Bank — the country’s sixth-largest lender — which focuses on wealth management.
If you like your comedy with a side of heart-warming feels and poignant cultural commentary, please look no further than The Big Sick, about a comedian who falls in love with a heckler. Their backgrounds could not be more different, which is relatable to anyone in a mixed race relationship.
I am afraid to go out in the sun now because of the holes in the ozone. I am afraid to breathe the air because I don't know what chemicals are in it. 我现在害怕晒太阳,因为臭氧层出现了空洞。我现在害怕呼吸空气,因为我不知道那里有多少化学物质。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 深圳:8月二手楼成交首破7000套
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

统筹城市地上地下建设,再开工建设城市地下综合管廊2000公里以上,启动消除城区重点易涝区段三年行动,推进海绵城市建设,使城市既有“面子”、更有“里子”。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
体操、蹦床、竞技体操、艺术体操、
Tesla:In an effort to blunt criticism about slow refueling times for battery-powered cars, Tesla TSLA -1.54% starts to roll out of a network of battery-swap stations. CEO Elon Musk must hope he can outdo Shai Agassi’s Better Place, which tried to build a whole company around battery-swaps before going bankrupt in 2013.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

2016年上榜的全球十亿美元级富豪共计1810名,位居次席的是Zara创始人阿曼西奥·奥特加,商界巨擘沃伦·巴菲特紧随其后,埃卢则是位居本榜单的第四名。
6. It’s not that the story ended badly; it’s that we expect too much of the story.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

He slipped a note through the door with the message "People stuck inside, please ask the property management for help," and hoped someone would pick it up and act on it.
Country's biggest stars gathered in Las Vegas on Sunday for the 2013 Academy of Country Music Awards.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 个税起征点提至5000元有望10月实现
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

But because I can’t help but hope that with the end of “Mad Men” comes the end of a period in fashion that has seen designers become trapped in the past to an almost stifling degree. At least the past as it looked in the 1960s (which in the beginning, let us not forget, looked a lot like the late 1950s) and early ’70s.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

读:挨批课。上课时赶上老师心情不好,念一段巨长的诗史批评你。这种方法确实是超凡脱俗,不同一般。E张黄色pic-超凡脱俗,不同一般的
SAN JUAN, Puerto Rico (AP) — Puerto Rico’s new governor was sworn in Monday as the U.S. territory prepares for what many believe will be new austerity measures and a renewed push for statehood to haul the island out of a deep economic crisis.
Gitanjali Rao was selected from 10 finalists who had spent three months collaborating with scientists to develop their ideas.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

人的身体是十分脆弱的,有些娇弱的器官一旦破坏就永远难以复原。幸运的是,世界各地的研究人员都在研究能替代我们身体部位的生化机械器官。
According to the financial data provider Wind Information Co Ltd, listed companies in China's A-share market earned 2.47 trillion yuan in profits last year. Of those listed companies, 2000 plan to pay out 700 billion yuan to their shareholders.
2016年的欧洲杯足球赛,俄罗斯与英国球迷因其粗鲁及流氓行为一直占据新闻头条。
TV soaps regularly top the TV ratings but the highest trending show of 2012 was the BBC kids' show 'Mike The Knight' that beat US terror drama 'Homeland' and 'Towie.'

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

One of the main strengths of the LBS programmes is the wide range of students from different countries. More than 90 per cent in its 2015 MBA cohort were from overseas, coming from about 60 different countries.
Enrollment: 388

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

时间:2010-03-31 编辑:vicki
Farewell to Cassini
公众宗教研究机构与宗教新闻通讯社联合开展的这项调查显示,不同政治派别和不同宗教信仰的人们对于恶劣天气的观念存在分歧,今年已经发生了多起严重的高温和干旱灾害。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

豆瓣网友“Amy”称:“他们是神仙。除了谈情说爱,就不能干点别的吗?”
Meanwhile, he was being ferried around the globe to tech conferences, getting introduced to other potential investors. D'Aloisio made a remarkable impression on everyone he crossed paths with. 'He has an eerie maturity,' says Andrew Halls, headmaster of the King's College School in Wimbledon, which D'Aloisio has attended since he was 11. 'He has an extraordinary articulateness in the face of situations that, for me, even as a 54-year-old, might be terrifying.'

Spotlight

Advertisements