Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Vocal duo: Thompson Square
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
adj. 确实的，保障的，有自信的 动词assure的过
Call Me By Your Name
Trends and targets in antiviral phototherapy
Best film and best director. Surprisingly, Nolan has never received a directing nomination from the Academy.
Executives in the finance and real estate industries have the highest pay, according to figures from the 1,894 listed companies that announced their annual financial reports in 2016.
“…brought his dog.”
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.
2. The 2012 Ig Nobel Peace Prize
ACE2 as a potential therapeutic target for pandemic COVID-19
Will José Antonio Meade be the next president of Mexico
Diagnostic technologies for COVID-19: a review
Last year was the hottest on earth since record-keeping began in 1880, scientists reported on Friday, underscoring warnings about the risks of runaway greenhouse gas emissions and undermining claims by climate change contrarians that global warming had somehow stopped.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
I can't stop thinking that these children are my age, that it makes a tremendous difference where you are born, that I could be one of those children living in the Favellas of Rio; I could be a child starving in Somalia; a victim of war in the Middle East or a beggar in India. 我永远不能忘记这些和我同龄的孩子，当你出生的时候，他和我们真的很不相同，我也许生活在贫民窟，也可能是终日饿着肚子的小孩，也可能是中东战争的牺牲品，或者印度的小乞丐。
Las Vegas Shooting
Together, the world’s 10 highest-paid actresses tallied a combined $205 million between June 1, 2015 and June 1, 2016, before management fees and taxes, Forbes said.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
This year, the average sales price for an apartment in New York City topped $1 million, a milestone with far-reaching implications. As the city’s population soars, prices and buildings are rising in neighborhoods that missed the last housing boom.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Official data indicates a total of 81 feature length films, including 47 Chinese titles, surpassed the 100 million yuan box office threshold.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Summly and Yahoo refused to comment on the deal’s terms.
Influenza neuraminidase: A druggable target for natural products
In fact, create a hard and fast rule to keep work and job searching separate. That means no sneaking out for a phone interview. No browsing job boards. No applying or networking with your work email address. "You don't watch porn at work, and you don't work on your résumé at work," Kay says. "You just don't."
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
37| “Anomalisa” (Charlie Kaufman/Duke Johnson)|
She was also recognised for being the youngest recipient of the Ripple of Hope Award from the Robert F. Kennedy Center for her charity work.
The role of biosensors in the detection of emerging infectious diseases
Despite it being not that different from the typical bottle opener, the BOx does have a nice design made with stainless steel and solid wood.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Ms Lewis urged people to contact family, neighbours or an animal shelter if they were no longer able to care for their pets.
But the change in Wall Street’s — and Silicon Valley’s — appreciation of Mr Cook is down to more than just the 70m iPhones Apple is expected to sell this quarter or the $42bn in sales generated in the previous.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
St. Vincent “Digital Witness” (Loma Vista/Republic)
This makes China the country with the second most number of universities included in the Global 400 Subjects, according to the QS rankings. This is only after the United States, which has 164 universities included in the Global 400 subjects. The UK comes third at 78 universities.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
The fastest growing start-ups tend to be global in their outlook. The immigration restrictions already imposed by President Trump in the US and those under consideration as part of the UK’s separation from the EU are likely to be a hindrance in the coming year for hiring.
Inhibition of SARS coronavirus helicase by bismuth complexes
2006年，哈茨与现任丈夫凯文共同创办了在线票务平台Eventbrite。自成立以来，这家公司先后从红杉资本（Sequoia Capital）和老虎全球基金（Tiger Global Management）等公司获得了总计1.4亿美元的投资。今年9月，它的票务销售总额达到了20亿美元。创业让哈茨不得不在与人沟通时运用坦率、且具有合作性的对话方式。她说：“我必须学会如何寻求帮助。所有人都认为创业是勇敢的举动，但我认为，更需要勇气的事情是，把自己摆到众人面前，同时努力达成协作。”
Yet institutions matter, too, because they set the rules of the game.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
STEP 9: BE SURE to tell everyone to shut up on a daily basis, it's endearing you know
The 25 most common passwords have been released by Splashdata which makes password management applications.
Will the UK economy be the slowest-growing in the G7
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Manufacturing has held up better, with profits growing 6.5 per cent, while profits from utilities such as electricity, heat and water grew 17 per cent, boosted by lower energy prices.
“Selling out!” “Pandering to the Americans!” The cries went up immediately when the official selection was announced. The list of directors crossing over to make films in English was a long one including the Italians Matteo Garrone and Paolo Sorrentino, Yorgos Lanthimos of Greece, Norway's Joachim Trier and even Guillaume Nicloux of France, a country whose cultural establishment is highly sensitive to the creeping Anglophone menace. The argument goes that Cannes is supposed to be a haven for world cinema; for English, there is Hollywood. But does it really matter? Films at Cannes in languages other than French or English play with subtitles in both languages – and that's a lot of text to deal with.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
China's Ministry of Education (MOE) said at a news conference that most of the world's foreign students who study abroad are from China.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Song “Embrace Happiness”(Kelly Chen)
The Jungle Book will be released worldwide on April 15, 2016.
An Obama tweet, published in August after racial violence rocked Charlottesville, Virginia was the second most-shared this year, according to Twitter, with more than 1.7 million retweets.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
China's 16 listed banks have cut their dividend payouts for the past year amid slowing net profit growth.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
8. “Mad Max: Fury Road”(George Miller)
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
WhatsApp had been particularly ad-averse before its sale to Facebook. CEO Jan Koum kept a note from co-founder Brian Acton taped to his desk to remind him of the company’s core values. It read: “No Ads! No Games! No Gimmicks!”
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.
20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告：“如果你上亚马逊，看到什么精彩的黑白电影卖三美元，或者其他什么外国电影和鲜为人知的电影，赶快买下来，因为它就要绝版了，他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式，迪克森警告说。而下载的美丽新世界（又名电子销售）明年将是好年头。
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
1)Thank You: Common courtesy? Sure. But tell me this: When was the last time you forgot (or rejected) gratitude? Whether given in private or public, a sincere ‘thanks’ creates goodwill. Don’t forget your mother’s advice: “Say please.” People are always happier doing a favor than taking an order.
Anyone can have a bad day at the office, but this disappointing performance at Christie’s followed an old masters sale in July that took in 19 million against a low estimate of 31.5 million.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
It is the eighth straight year that the metropolis has led Chinese cities in terms of consumer spending.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
尽管英国商学院的排名平均上升了两位，但法国商学院的排名平均下降了一位——法国是商学院数量最多的欧洲国家。里昂商学院(EMLyon Business School)由于跌出MBA榜单之外，整体排名下降了15位，同时北方高等商学院(Edhec Business School)由于未能进入EMBA榜单，整体排名下降了8位。
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A total of 1,300 fugitives suspected of economic crimes, 347 of whom were corrupt officials, returned to China from abroad to face justice last year, according to the country's top discipline watchdog.
A modular microarray imaging system for highly specific COVID-19 antibody testing
China will "fasten the seat belt" and prevent any "acute outburst" of financial risks on the track for maintaining medium-high growth speed.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
I am so excited to be hosting the Oscars for the second time. You know what they say - the third time's the charm.
US News also offers subject-focused rankings, which include popular fields such as computer science, economics and business and engineering.
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
4. Outsourcing placement services.
Scientists have long investigated stem cells' potential for growing hearts, and they reached a major milestone this year when they created heart tissue than can beat on its own.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
In 2002, Marc Cherry (the creator of Desperate Housewives) was watching the news with his mother in her home. The lead story on the news that day (and many days before) was the Andrea Yates trial. Andrea was on trial for drowning her five children in the bathtub. Marc turned to his mother and asked, "Could you imagine a woman being so desperate that she would murder her own children?"
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
He was responsible for monitoring how many cupcake aficionados were allowed in the store at one time. Of course Magnolia Bakery isn't exactly complaining. The store proudly displays memorabilia from the show on the walls of their many locations. Today, Magnolia Bakery is known for their banana pudding, but they will always owe their initial success to Carrie Bradshaw and a red velvet cupcake.
Dua Lipa, 'Dua Lipa'
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
People (read: your boss) will notice if you go from sporting a uniform of jeans and a T-shirt to showing up in a tailored suit on interview day. This is all the more reason to take the day off from work to interview, but if you don't, dress as usual at the office. And then, Foss says, "leave the premises, and stop in a McDonald's parking lot on the way to the interview to change."
Others are Ouyeel, a unit of Shanghai Baosteel Group that provides financing for steel traders; and Small Entrepreneur, part of China Merchants Bank — the country’s sixth-largest lender — which focuses on wealth management.
If you like your comedy with a side of heart-warming feels and poignant cultural commentary, please look no further than The Big Sick, about a comedian who falls in love with a heckler. Their backgrounds could not be more different, which is relatable to anyone in a mixed race relationship.
I am afraid to go out in the sun now because of the holes in the ozone. I am afraid to breathe the air because I don't know what chemicals are in it. 我现在害怕晒太阳，因为臭氧层出现了空洞。我现在害怕呼吸空气，因为我不知道那里有多少化学物质。
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
Tesla:In an effort to blunt criticism about slow refueling times for battery-powered cars, Tesla TSLA -1.54% starts to roll out of a network of battery-swap stations. CEO Elon Musk must hope he can outdo Shai Agassi’s Better Place, which tried to build a whole company around battery-swaps before going bankrupt in 2013.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
6. It’s not that the story ended badly; it’s that we expect too much of the story.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
He slipped a note through the door with the message "People stuck inside, please ask the property management for help," and hoped someone would pick it up and act on it.
Country's biggest stars gathered in Las Vegas on Sunday for the 2013 Academy of Country Music Awards.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
But because I can’t help but hope that with the end of “Mad Men” comes the end of a period in fashion that has seen designers become trapped in the past to an almost stifling degree. At least the past as it looked in the 1960s (which in the beginning, let us not forget, looked a lot like the late 1950s) and early ’70s.
Anti-HIV drug repurposing against SARS-CoV-2
SAN JUAN, Puerto Rico (AP) — Puerto Rico’s new governor was sworn in Monday as the U.S. territory prepares for what many believe will be new austerity measures and a renewed push for statehood to haul the island out of a deep economic crisis.
Gitanjali Rao was selected from 10 finalists who had spent three months collaborating with scientists to develop their ideas.
Length-scale dependence of protein hydration-shell density
According to the financial data provider Wind Information Co Ltd, listed companies in China's A-share market earned 2.47 trillion yuan in profits last year. Of those listed companies, 2000 plan to pay out 700 billion yuan to their shareholders.
TV soaps regularly top the TV ratings but the highest trending show of 2012 was the BBC kids' show 'Mike The Knight' that beat US terror drama 'Homeland' and 'Towie.'
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
One of the main strengths of the LBS programmes is the wide range of students from different countries. More than 90 per cent in its 2015 MBA cohort were from overseas, coming from about 60 different countries.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Farewell to Cassini
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Meanwhile, he was being ferried around the globe to tech conferences, getting introduced to other potential investors. D'Aloisio made a remarkable impression on everyone he crossed paths with. 'He has an eerie maturity,' says Andrew Halls, headmaster of the King's College School in Wimbledon, which D'Aloisio has attended since he was 11. 'He has an extraordinary articulateness in the face of situations that, for me, even as a 54-year-old, might be terrifying.'